PRIMARY AGE-RELATED TAUOPATHY
A neurological disease in people that have symptoms similar to Alzheimer’s disease, but lack the amyloid plaque in the brain that is considered a hallmark of that disease.
The newly coined disease is called primary age-related tauopathy (PART). Patients with PART have symptoms of cognitive impairment synonymous with Alzheimer’s, but only have another type of protein in the brain called tau that can contribute to memory loss when it malfunctions.
Recent diagnostic tests and biomarkers found in cerebral spinal fluid indicate that a large percentage of patients with mild cognitive impairment — as high as 25% in some studies — may have PART considering they have tau protein but no amyloid.
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